Introduction of Carcinogenesis

by Kok Siong Chen on June 14, 2010

Carcinogenesis or tumourigenesis is the process of which normal cells are transformed into cancer cells, where they acquired the ability to proliferate abnormally and invade surrounding tissues (Atif and Peter, 2006).

carcinogenesis 300x187 Introduction of Carcinogenesis

All about Carcinogenesis

Cancer is a group of diseases that are characterized by uncontrolled cellular growth, enhanced angiogenesis and reduced programmed cell death (David and Lisa, 2008). Because of carcinogenesis, cancer cells can spread to other locations throughout the body, where they grow and upset normal bodily functions. It is known as metastatic spread where the cells are dispersed around the blood stream that formed leukemia or the lymphatic system that formed lymphoma or when some of the cancer cells clump together to form solid tumours (Arthur and Gary, 2009). As part of carcinogenesis, the disruptive behaviours of cancer cells are because of the changes in their genomes and gene expression that result in disruption of normal regulatory signalling pathways (Atif and Peter, 2006).

According to cancer research, about 200 varieties of cancer disease have been described. The cancer diseases can be grouped in four main types: carcinomas, sarcomas, leukemias and lymphomas, and neuroectodermal. Carcinomas are solid cancers which arise from the epithelial cells that line the inner and outer surfaces. Sarcomas are solid cancers that developed from the connective tissue cells that form our body structures. Leukemias and lymphomas are cancers caused by white blood cells (Arthur and Gary, 2009). Neurodectodermal is another group of nonepithelial tumours which arise from cells that form various components of the central and peripheral nervous system.

There are many risk factors of cancer which include both external and internal factors. Some of the examples of external factors are tobacco, exposure to chemical, radiation, and infectious organisms that can induce the development of cancer cell. On the other hand, the internal factors such as inherited mutations, hormones, immune conditions, and mutations that involved metabolism are the risk factors that have been implicated with the development of cancer cells. These causal factors may act together or in sequence to initiate or promote carcinogenesis (American Cancer Society, 2008).

In conclusion, carcinogenesis will harm our body. However, we can still prevent it from happenning. Live healthy with balanced meal is one of the best way to get rid of carcinogenesis. Recently, many cancer researchers recommend people to consume more vegetables. I have converted myself to be a vegetarian since last year. You may do so. At least, reduce the amount of meat in your meal. May you be healthy and well always! :)

This is a part of the literature review of my final year project thesis. I wish to share with you all what i have done on it.

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1 miao miao June 15, 2010 at 10:56 am

mimi!!!!
hello!!
miao miao´s last blog ..My familyMy ComLuv Profile

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